This volume features a selection of technical papers presented at the workshop “The Fifth Workshop on Interdisciplinary Sciences (WIS 2023)". Contributions from esteemed researchers and academics in applied mathematics, AI, and statistics offer valuable insights into their latest research. The papers also delve into interdisciplinary applications, spanning fields such as agriculture and economics, with strong emphasis on data analysis techniques. We hope this proceedings volume will serve as a valuable resource for scholars, researchers, and practitioners interested in the recent advancements and emerging trends in interdisciplinary sciences.