Safety engineering is an engineering discipline with an interdisciplinary and application-oriented focus. The main focus is on the knowledge-based development and application of methods for the analysis and prevention of hazards and the minimization of remaining hazards to human safety and health and to the environment, particularly in connection with technically complex products, systems and processes. At the University of Wuppertal, Germany, safety engineering has been an established teaching and research area for 50 years. It covers a wide area of subjects from e. g. plant and product safety over energy efficiency to safety and quality law. This book provides an overview of the fundamentals, methods and current research results as well as examples of the application of teaching and research activities in safety engineering at the University of Wuppertal. The target groups are therefore equally engineers, scientists and engineering students who deal with questions of safety engineering in an application-oriented and scientific context.