During his long and distinguished career, J. Rowland Higgins (1935-2020) made a substantial impact on many mathematical fields through his work on sampling theory, his deep knowledge of its history, and his service to the community. This volume is a tribute to his work and legacy, featuring chapters written by distinguished mathematicians that explore cutting-edge research in sampling, approximation, signal analysis, and other related areas. An introductory chapter provides a biography of Higgins that explores his rich and unique life, along with a bibliography of his papers; a brief history of the SampTA meetings – of which he was a Founding Member – is also included. The remaining articles are grouped into four sections – classical sampling, theoretical extensions, frame theory, and applications of sampling theory – and explore Higgins’ contributions to these areas, as well as some of the latest developments.