Technology-based startup enterprises are an increasingly important part of the business landscape in Asia and the Pacific. By applying innovative technologies to create new products and services, they can make a significant contribution to economic development while generating social and environmental benefits. However, to survive and then thrive, tech startups require an enabling ecosystem that includes supportive government policy, and adequate access to capital, skilled personnel, and quality digital infrastructure. This report examines Singapore’s vibrant tech startup ecosystem and identifies key lessons that can inform the efforts of Indonesia, Malaysia, and Thailand to nurture and develop their tech startups. The report focuses on four key sectors: climate change and environment, agriculture, education, and health.