This eBook is the premier volume of our "Mental Illness/Central Nervous System" series, focussing specifically on " SUBSTANCE-RELATED AND ADDICTIVE DISORDERS". This eBook release encompasses diagnoses such as alcohol-related disorders, cannabis-related disorders, hallucinogen-related disorders, inhalant use disorder, opioid-related disorders, sedative-, hypnotic-, or anxiolytic-related disorders, stimulant-related disorders, and tobacco-related disorders, and others. The content comprises a total of 511 "MCQs with Guiding Answers" and 627 "Linked References". This eBook also contains numerous "Study Highlights or Summary Keypoints" alongside the "CLINICAL PRACTICE INSIGHTS" section. Our primary clients include medical professionals, clinical pharmacists or PharmDs, nurses, and various other individuals in the healthcare sector, such as mentors, residents, and students. We adhere to conventional design principles for all our sequential eBook publications to circumvent the trend of "hypercoloremia mania" in eBook design. This predominantly employs the official black and white colour scheme. This publication resulted from a collaborative effort with my skilled and dedicated coauthors, namely PharmDs Arwa Alashqar, Duaa Alqhaiwi, Najd Alyasjeen, Kariman Hatem, Leen Albishawi, Eman Awwad, Farah Qaryouti, Dana AlTaweel, Alia' Saidan, Areej Al-Manasyeh, and Marah Hussein.

Corresponding author; Clinical Pharmacy Specialty “MOH’D NOUR” BANI-YOUNES”, MSc Clinical Pharmacy, BCPS, BCCCP, BCNSP, BCACP, BCIDP