Tell Ahmar – also known as Masuwari, Til Barsib and Kar-Shalmaneser in the first millennium BCE – was first inhabited in the sixth millennium, during the Ubaid period, and progressively developed to become a regional center and, in the eighth and seventh centuries, a provincial capital of the Assyrian empire. Remains from the third millennium (a temple and a funerary complex), the second millennium (an administrative complex and well-preserved houses) and the first millennium (an Assyrian palace and elite residences) are particularly impressive.

The book offers an archaeological and historical synthesis of the results obtained by the excavations of François Thureau-Dangin (1929–1931) and by the more recent excavations of the universities of Melbourne (1988–1999) and Liège (2000–2010). It presents a comprehensive and diachronic view of the evolution of the site, which, by its position on the Euphrates at an important crossroads of ancient communication routes, was at the heart of a game of cultural and political interference between Mesopotamia, the Mediterranean world and Asia Minor.