Like a latter-day Gregor Samsa, Professor David Kepesh wakes up one morning to find that he has been transformed. But where Kafka's protagonist turned into a monstrous cockroach, the narrator of Philip Roth's fantasy has become a 155-pound female breast.

What follows is a deliriously funny yet moving exploration of the full implications of Kepesh's metamorphosis; audacious, heretical - as darkly hilarious as it is existentially unnerving - making new the silliness, triviality and wonderful meaninglessness of lived human experience.