The Douay–Rheims Bible,also known as the Rheims–Douai Bible or Douai Bible, and abbreviated as D–R and DRB) is a translation of the Bible from the Latin Vulgate into English made by members of the English College, Douai, in the service of the Catholic Church.

The New Testament portion was published in Reims, France, in 1582, in one volume with extensive commentary and notes. The Old Testament portion was published in two volumes twenty-seven years later in 1609 and 1610 by the University of Douai. The first volume, covering Genesis through Job, was published in 1609; the second, covering Psalms to 2 Machabees plus the apocrypha of the Vulgate was published in 1610. Marginal notes took up the bulk of the volumes and had a strong polemical and patristic character. They offered insights on issues of translation, and on the Hebrew and Greek source texts of the Vulgate.

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