This book constitutes the thoroughly refereed proceedings of the 39th National Conference of Theoretical Computer Science, NCTCS 2021, held in Yinchuan, China, in July 2021.

The 67 full papers were carefully reviewed and selected from 145 submissions, and 14 of them were selected for the volume. The papers present recent research in the areas of information hiding, data detection and recognition, system scheduling, time series prediction, and formal analysis.